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Mirari Biosciences Awarded SBIR Grant from National Institutes of Health to Apply MASCTM Technology To Drug Discovery

Rockville, MD - September 1, 2004 - Mirari Biosciences received a Small Business Innovation Research (SBIR) grant from the National Institutes of Health (Bethesda, MD). The grant allows Mirari to apply its novel microwave-based chemistry and detection method Microwave-Accelerated Surface ChemistryTM (MASCTM) to the discovery and characterization of new drug candidates via the process of combinatorial chemistry. MASCTM will be used to greatly accelerate the synthesis of diverse libraries of drug-like molecules on "chips" the size of a stick of gum. MASCTM will then be used to sensitively and quickly observe the interactions of the chip molecules with proteins, such as those relevant to disease. These studies may lead to a rapid and easy means of synthesizing and evaluating the function of drug candidate libraries.